Bioactive Small Molecules
Cayman Chemical Leu144Arg147-PLP139-151 5mg
A mutant fragment of PLP peptide; increases spleen levels of IL-4 in mice when administered at 50 UG emulsified in CFA as an immunization; inhibits Th1 cell activation in vitro but not in vivo, where it induces the generation of regulatory T cells; delays the onset of PLP (178-191)-, MOG (92-106)-, or MBP-induced EAE in mice
Medchemexpress LLC HY-12041 100mg , SP600125 CAS:129-56-6 Purity:>98%
HY-12041 100mg SP600125 CAS: 129-56-6 SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 inhibits autophagy and activates apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC gp91ds-tat P1213-5MG
gp91ds-tat a peptide inhibitor for NADPH oxidase assembly is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide The tat sequence facilitates the entry of this peptide into cells
Selleck Chemical LLC Cyclizine hydrochloride E4905-1G
Cyclizine hydrochloride is an antagonist of the H1 histamine receptor used for the treatment and prevention of vertigo and motion sickness It also exhibits antihistaminic properties
Selleck Chemical LLC T863 S0359-25MG
T863 (DGAT-3) is a potent selective and orally active inhibitor of Acyl-CoA diacylglycerol acyltransferase 1 (DGAT1) tht acts on the acyl-CoA binding site of DGAT1 and inhibits DGAT1-mediated triacylglycerol formation in cells
Selleck Chemical LLC Imeglimin S9925-5MG
Imeglimin (EMD 387008 IMEG PXL 008 RVT-1501) Hydrochloride is a new class of oral glucose-lowering agents Imeglimin normalizes glucose tolerance and insulin sensitivity by preserving mitochondrial function from oxidative stress and favoring lipid oxidation in liver of HFHSD mice
Selleck Chemical LLC ON-013100 E7822-1MG
ON-013100 is a benzylstyrylsulfone antineoplastic agent and a potent mitotic inhibitor It inhibits CDK4 and cyclin D1 expression while suppressing MDM2 and reducing p53 levels disrupting mitogenic signaling and enhancing its anticancer activity
Selleck Chemical LLC DiI E4783-25MG
DiI (DiIC18(3)) is a lipid-soluble fluorescent dye that traces neuronal pathways through retrograde and anterograde transport in neurons It labels cell bodies axons dendrites and dendritic spines offering high brightness slow fading and long-lasting persistence without leakage It is employed to investigate brain connectivity including in postmortem human brain tissue
Selleck Chemical LLC Laninamivir E4879-1MG
Laninamivir(R-125489) is a potent inhibitor of influenza neuraminidase(NA)with IC50s of 0 90 nM 1 83 nM and 3 12 nM for avian H12N5 NA (N5) pH1N1 N1 NA (p09N1) and A/RI/5 /1957 H2N2 N2 (p57N2) respectively It exhibits long-acting anti-influenza virus activity
Selleck Chemical LLC Ternate buttercup rootExtract E3473-5MG
Ternate Buttercup Root Extract is extracted from the roots of Ternate Buttercup which boosts the activity of the immune system reduces inflammation scavenges damaging particles known as free radicals and destroys cancerous cells
Medchemexpress LLC 6-(3-(tert-butyl)-1H-pyrazol-5-yl)-N-(3-fluoro-4-methyl-2-(7-oxo-...)nicotinamide | 2729996-45-4 | 98.9% | 455.48 g/mol | C26H22FN5O2 | 5 MG
GNE-9815 is a small-molecule Type II pan-RAF kinase inhibitor intended for preclinical research use only. It modulates RAF-mediated MAPK signaling and has been used in studies of KRAS-mutant cancers. The compound is supplied as a solid with high chemical purity and requires low-temperature storage.
- High purity (98.9%) suitable for biochemical and cell-based assays.
- Molecular weight 455.48 g/mol; formula C26H22FN5O2.
- Available in small research pack sizes, such as 5 mg.
- Storage recommendations: powder at -20°C; in solvent store at -80°C for long term.
- For research use only; not for human or veterinary use.
Medchemexpress LLC 5,8,11,14-Eicosatetraenamide, N-(2-chloroethyl)-, (5Z,8Z,11Z,14Z)- | 220556-69-4 | 96.2% | 365.98 | 25 MG
ACEA (arachidonyl-2'-chloroacetamide) is a synthetic organic compound that functions as an agonist for the cannabinoid receptor CB1. It influences the endocannabinoid system, which is responsible for regulating various physiological processes such as appetite, pain perception, mood, and memory. Additionally, ACEA serves as a biochemical reagent suitable for life science research applications, either as a biological material or an organic compound.
- Acts as an agonist of the cannabinoid receptor CB1.
- Affects the endocannabinoid system, regulating appetite, pain perception, mood, and memory.
- Useful as a biochemical reagent for life science research.
- For research use only.
Selleck Chemical LLC AZD-5462 E1995-100MG
AZD-5462(Example 1) is a modulator of RXFP1 the cognate receptor for human relaxin that belongs to the GPCR family 1c number AZD-5462 exhibits anti-fibrotic and anti-inflammatory properties
Cayman Chemical ANTIBODY DInacIclIb 5mg
A pan-CDK inhibitor (IC50s = 3, 1, 1, and 4 nM for CDK1, CDK2, CDK5, and CDK9, respectively) that inhibits DNA synthesis in A2780 ovarian cancer cells (IC50 = 4 nM); 5 mg/kg prevents tumor growth by 50% in an A2780 ovarian carcinoma mouse xenograft model; active against a broad spectrum of human tumor cell lines in vitro (IC50s = 7-17 nM)
Medchemexpress LLC Fraxin (Fraxoside) | 524-30-1 | 370.31 | 100 MG
Fraxin, also known as Fraxoside, is isolated from Cortex Fraxini. It is a glucoside of fraxetin and has been reported to possess potent anti-oxidative stress, anti-inflammatory, and antimetastatic properties. Fraxin exhibits its antioxidative effect by inhibiting the cyclo AMP phosphodiesterase enzyme.
- Isolated from Cortex Fraxini
- Glucoside of fraxetin
- Exerts potent anti-oxidative stress action
- Possesses anti-inflammatory properties
- Shows antimetastatic properties
- Inhibits cyclo AMP phosphodiesterase enzyme